A small glass of wine has around 100 calories, a medium contains approximately 140 calories, and a large one contains approximately 200 calories. A bottle of wine comprises 750ml (75cl), thus a bottle of wine contains 600 calories on average. In the same way, many individuals are curious about the caloric content of a 750-ml bottle of . A standard bottle of wine contains 25.4 ounces (750 milliliters). Given that one ounce of dry red or white wine has around 25 calories, a complete bottle of wine contains approximately 635 calories. Chardonnay has 118 calories and a 14.5% alcohol content.